Préime Ultra B

Préime Transdermal Ultrasound

Sonophoresis uses transdermal ultrasound to significantly improve the absorption and penetration of dermaceuticals into the skin

Enhancing Skincare Delivery with Sonophoresis

Préime Ultra B harnesses the power of transdermal ultrasound to significantly improve the absorption and penetration of active ingredients into the skin. This innovative process, known as sonophoresis, uses ultrasound waves to enhance the delivery of beneficial skincare products deep into the targeted layers of the skin — far beyond what manual application alone can achieve.

The science behind this is well established. Ultrasound energy creates temporary micro-channels within the skin’s outer barrier. These channels allow active ingredients to bypass the stratum corneum — the layer that normally limits how much a topical product can penetrate — and reach the deeper dermal structures where they can have a meaningful effect.

The result is a significant difference in efficacy. The same ingredient applied by hand and delivered via sonophoresis is not equivalent. Studies have demonstrated penetration rates many times higher when ultrasound is used as the delivery mechanism.

This matters because most skincare actives — including hyaluronic acid, peptides, and antioxidants — work best when they reach the dermis. Surface-level application produces surface-level results. Sonophoresis changes that equation.

The process is gentle. There is no discomfort, no downtime, and no disruption to the skin’s structure. The micro-channels close naturally after treatment. What remains is a deeper distribution of active ingredients and a skin environment better equipped to respond to them.

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How Does Sonophoresis Work?

Sonophoresis involves the use of high-frequency sound waves (typically 1-3MHz) to create gentle vibrations within the skin’s surface and deeper layers. These vibrations have multiple effects:

  1. Disrupting the Stratum Corneum: The sound waves temporarily alter the structure of the skin’s outer layer, creating microscopic channels that allow skincare molecules to penetrate more easily.
  2. Cavitation Effect: The ultrasound energy generates tiny microbubbles within the intercellular space. These bubbles expand and contract rapidly, effectively “pushing” or “sucking” molecules deep into the skin.
  3. Increased Microcirculation and Lymphatic Drainage: The thermal effects of ultrasound improve blood flow and lymphatic drainage, further supporting deep absorption and enhanced skin rejuvenation.
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What Are the Benefits of Sonophoresis?

Sonophoresis offers several advantages over traditional skincare application and even injectable treatments:

  • Enhanced Product Absorption – Increases the penetration of active ingredients that would otherwise struggle to pass through the skin.
  • Targets Large Areas – Unlike injections, which focus on small treatment sites, sonophoresis can treat the face or body area in one session.
  • Non-Invasive – No needles required, making it a comfortable and safe option for all skin types.
  • Higher Concentration of Active Products – Ensures deep, targeted delivery without the risk of systemic absorption, which can cause unwanted side effects.
  • Versatile and Effective – Can be used for a range of skin concerns, from hydration and rejuvenation to hyperpigmentation, hair treatments, and wound healing.

Recommended Dermaceuticals for Sonophoresis

Certain skincare ingredients benefit significantly from ultrasound-enhanced delivery. Some of the most effective include:

  • Préime Polynucleotide – A revolutionary rejuvenating agent normally used in injectables. Sonophoresis allows it to be delivered deeply without needles, covering a wider treatment area for maximum anti-ageing benefits.
  • Exosomes – Tiny, cell-derived vesicles that boost skin regeneration and repair at a cellular level.
  • Hyaluronic Acid, Vitamin C, Peptides & Growth Factors – Hydrating, brightening, and strengthening ingredients that deeply nourish the skin when delivered via ultrasound.

What is Sonophoresis Used For?

Sonophoresis is already widely used in medicine and physiotherapy to deliver drugs directly to muscles and joints. In aesthetics and dermatology, it has become an exciting needle-free alternative for:

  • Skin Rejuvenation – Reduces fine lines and wrinkles by deeply infusing hydrating and collagen-boosting ingredients.
  • Hyperpigmentation – Helps to break down melanin clusters and brighten the complexion.
  • Hair and Scalp Treatments – Supports hair growth and scalp health by enhancing the absorption of targeted serums.
  • Wound Healing – Accelerates tissue repair and regeneration, aiding recovery from scars or skin damage.

The Future of Transdermal Ultrasound

Préime Ultra B represents a major step forward in non-invasive skincare technology. By using ultrasound waves to deeply and effectively deliver powerful rejuvenating ingredients, it bridges the gap between topical skincare and injectable treatments—without the discomfort of needles or the risk of high systemic concentrations.

Ready to experience the next level of skincare innovation? Discover how Préime Ultra B can transform your skin today.